2024-2028 Steering Committee Candidate:

Changsheng Liu

Biosketch:

Affiliation: East China University of Science and Technology (ECUST)

Prof. Changsheng Liu holds the prestigious title of Cheung Kong Scholar Professor of Biomaterials at East China University of Science and Technology (ECUST), China. He is concurrently an Academician of the Chinese Academy of Sciences, a Fellow of the Chinese Academy of Medical Sciences, an International Fellow of Biomaterials Science and Engineering (IFBSE) of the Union of Society for Biomaterials, and a Fellow of the American Institute for Medical and Biological Engineering (AIMBE). He is the Chief Scientist of the National Major Scientific Research Program, and an academic leader of the Innovative Research Group of the National Natural Science Foundation of China.

Prof. Liu holds various academic positions, including member of the Material Science Committee and International Cooperation Committee of the Ministry of Education, Former Chairman of the China Biomaterials Society, and Chairman of the Shanghai Silicate Society.

He graduated with a bachelor’s degree from Hubei University in 1989, obtained a master’s degree in science from ECUST in 1992, and earned a doctoral degree in engineering from ECUST in 1996. From 2000 to 2008, he served as the director of the Biomaterials Research Institute at ECUST. Since 2001, he has successively held the positions of director of the Medical Biomaterials Engineering Research Center of the Ministry of Education and director of the Key Laboratory of Ultrafine Materials Preparation and Application. He served as the dean of the School of Materials Science and Engineering in ECUST from December 2009 to November 2015, and was Vice President of the ECUST from July 2015 to May 2019. Since June 2019, he has been serving as the President of Shanghai University.

Prof. Liu’s research primarily focuses on biomaterials, including materials for tissue repair and regeneration, nano-biomaterials, injectable biomaterials, and controlled release of drugs/bioactive factors. He has developed various active bone repair materials and new technologies for growth factor preparation and material activation. He was the first in China to develop self-curing calcium phosphate cement for bone repair, obtaining the first registration certificate for such products and achieving widespread clinical application. Using genetic engineering techniques, he utilized prokaryotic organisms to manufacture bone morphogenetic protein-2 (BMP-2) and thereafter obtained composite material for bone repair with high osteogenic activity, which have been adopted by more than 1000 hospitals across the country, demonstrating their efficacy in clinical settings. In 2018, he pioneered the field of Materiobiology, which explores the biological characteristics of materials to provide bioactive cues and regulate microenvironments, leading to the creation of a biomaterial genome database and a theoretical framework for material development. Guided by Materiobiology, Prof. Liu has innovated a sulfated chitosan and designed a pentasaccharide sequence to engage anti-inflammatory macrophages and stimulate the secretion of endogenous vascular endothelial growth factor, directing therapeutic angiogenesis in ischemic conditions.

Prof. Liu has an extensive publication record with over 400 peer-reviewed journal articles?such as Nature Comm., Sci. Adv., PNAS, Adv. Mater., Chem. Rev. etc., 90 patents and invention disclosures (4 of which are authorized in the United States), and has contributed to 12 edited books and book chapters. His work has garnered a significant impact, with a citation count of 24,755 and an h-index of 79 on Google Scholar.

His outstanding innovations and contributions have been recognized with numerous honors, including the Special Prize of the Shanghai Award for Technological Invention, Bioactive materials Lifetime Achievement Award, the Second Prize of the National Natural Science Award (China), the Second Prize of the National Award for Science and Technology Progress (China), the Ho Leung Ho Lee Foundation Prize for Scientific and Technological Innovation, and the Silver Prize for Innovation and Excellence of INPEX in Medicines (US).

Prof. Liu also serves on the editorial boards of several esteemed journals, such as Biomaterials Translational as an Editor-in-Chief, and as a member of the editorial team for National Science Review, Life Medicine, SCIENCE CHINA Technological Sciences etc.

Vision & Purpose:

As a dedicated academic and a pioneer in the realm of biomaterials, my purpose and vision for the International College of Fellows are rooted in the belief that collaborative innovation and knowledge exchange are essential to advancing the frontiers of science and technology. My vision encompasses a global community of scholars and researchers who are committed to harnessing the transformative power of biomaterials for the betterment of human health and well-being.

First, my purposes for the International College of Fellows are summarized as follows,

Promoting Interdisciplinary Collaboration: I aim to foster an environment that encourages interdisciplinary collaboration, bringing together experts from diverse fields such as materials science, bioengineering, medicine, and computational modeling. By combining our collective knowledge and expertise, we can develop innovative solutions to the complex challenges associated with bone repair and tissue regeneration.

Advancing Biomaterials Research: My purpose is to drive the field forward by conducting cutting-edge research that not only addresses the current limitations of biomaterials but also anticipates future needs. Through rigorous investigation and experimentation, we can uncover new materials and techniques that offer improved biocompatibility, functionality, and efficacy in clinical applications.

Mentorship and Knowledge Dissemination: As a professional researcher, I am committed to mentoring the next generation of scientists and engineers, equipping them with the skills and insights necessary to excel in their careers. I also aim to disseminate our research findings and insights widely, ensuring that the benefits of our work reach the broader scientific community and ultimately, society at large.

My vision for the International College of Fellows:

Establishing a Global Biomaterials Hub: My vision is to see the International College of Fellows evolve into a leading global hub for biomaterials research. By establishing collaborative networks and partnerships, we can facilitate the exchange of ideas and resources, accelerating the pace of discovery and innovation.

Innovative Educational Programs: I envision the development of innovative educational programs that not only teach the fundamentals of biomaterials but also instill a sense of curiosity, creativity, and critical thinking. These programs will prepare our Fellows to be leaders in an ever-changing landscape, capable of addressing the evolving challenges of the 21st century.

Translating Research into Clinical Practice: A core aspect of my vision is to bridge the gap between research and clinical practice. By working closely with healthcare professionals and industry partners, we can ensure that our research translates into tangible benefits for patients, improving outcomes and enhancing the quality of life.

In conclusion, my purpose and vision for the International College of Fellows are to create a vibrant, collaborative, and forward-thinking community that is dedicated to pushing the boundaries of biomaterials research. Together, we can make significant strides in the field, contributing to a healthier and more prosperous future for all.

For this reason, I am eager and honored to accept the nomination and to contribute my expertise as a member of the Steering Committee.